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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLG2
All Species:
20
Human Site:
S65
Identified Species:
44
UniProt:
Q15700
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15700
NP_001136171.1
870
97552
S65
Y
V
L
Q
S
H
I
S
P
L
K
A
S
P
A
Chimpanzee
Pan troglodytes
XP_522127
870
97516
S65
Y
V
L
Q
S
H
I
S
P
L
K
A
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001098808
926
103319
T81
E
P
I
Q
P
V
N
T
W
E
I
S
S
L
P
Dog
Lupus familis
XP_542276
901
100149
H96
G
E
R
C
A
C
A
H
G
W
F
S
P
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91XM9
852
94785
S65
Y
V
L
Q
S
H
I
S
P
L
K
A
S
P
A
Rat
Rattus norvegicus
Q63622
852
94916
S65
Y
V
L
Q
S
H
I
S
P
L
K
A
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513847
646
71054
Chicken
Gallus gallus
XP_417217
975
109471
S169
Y
V
L
Q
S
H
I
S
P
L
K
A
S
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PYH7
881
98489
T65
P
N
R
L
C
L
S
T
T
D
S
P
H
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31007
970
106654
K65
L
T
L
L
D
D
S
K
S
I
Q
Q
K
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P54936
961
108794
V109
N
D
I
C
F
E
I
V
Q
R
A
S
N
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
52.3
87.5
N.A.
94.7
95.4
N.A.
70.3
85.3
N.A.
81.5
N.A.
43.5
N.A.
20.9
N.A.
Protein Similarity:
100
100
65.6
88.9
N.A.
95.7
96.3
N.A.
72.5
88
N.A.
88.1
N.A.
57.1
N.A.
40.5
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
100
100
N.A.
0
100
N.A.
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
13.3
N.A.
100
100
N.A.
0
100
N.A.
6.6
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
10
46
0
0
55
% A
% Cys:
0
0
0
19
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
10
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
10
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
46
0
10
0
0
0
0
10
0
0
% H
% Ile:
0
0
19
0
0
0
55
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
46
0
10
0
0
% K
% Leu:
10
0
55
19
0
10
0
0
0
46
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
10
10
0
0
10
0
0
0
46
0
0
10
10
46
10
% P
% Gln:
0
0
0
55
0
0
0
0
10
0
10
10
0
0
10
% Q
% Arg:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
46
0
19
46
10
0
10
28
55
10
0
% S
% Thr:
0
10
0
0
0
0
0
19
10
0
0
0
0
19
0
% T
% Val:
0
46
0
0
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% W
% Tyr:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _